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Remission From Behavioral Dysregulation in a Child With PTSD After Receiving Procedural Ketamine

Remission From Behavioral Dysregulation in a Child With PTSD After Receiving Procedural Ketamine

1 month ago · · 0 comments

– Anna C. Donoghue, Mark G. Roback, Kathryn R. Cullen Abstract Ketamine, an N-methyl-D-aspartate–type glutamate receptor antagonist, has long been used for anesthesia and has recently been investigated for its rapid antidepressant effects in adults with treatment-resistant depression and posttraumatic stress disorder (PTSD). We report a case of a child with PTSD and episodes of severe aggression […]

Ketamine research reports 75% success rate in treatment of long-term depression

Ketamine research reports 75% success rate in treatment of long-term depression

2 months ago · · 0 comments

Researchers looking into the use of ketamine say they have had a 75 per cent success rate in using it to treat long-term depression. “The results are startling,” says Melbourne University neuroscientist Associate Professor Graham Barrett, who has been studying depression for 30 years. “They’re not 100 per cent, there are people who don’t respond […]

Subanesthetic ketamine infusions for the treatment of children and adolescents with chronic pain: a longitudinal study

Subanesthetic ketamine infusions for the treatment of children and adolescents with chronic pain: a longitudinal study

2 months ago · · 0 comments

Background Chronic pain is common in children and adolescents and is often associated with severe functional disability and mood disorders. The pharmacological treatment of chronic pain in children and adolescents can be challenging, ineffective, and is mostly based on expert opinions and consensus. Ketamine, an N-methyl-D-aspartate receptor antagonist, has been used as an adjuvant for […]

How much ketamine is the right dosage for Treatment Resistant Depression?

How much ketamine is the right dosage for Treatment Resistant Depression?

2 months ago · · 0 comments

– Maurizio Fava, Marlene P. Freeman, Martina Flynn, Heidi Judge, Bettina B. Hoeppner, Cristina Cusin, Dawn F. Ionescu, Sanjay J. Mathew, Lee C. Chang, Dan V. Iosifescu, James Murrough, Charles Debattista, Alan F. Schatzberg, Madhukar H. Trivedi, Manish K Jha, Gerard Sanacora, Samuel T. Wilkinson, George I. Papakostas Abstract Numerous placebo-controlled studies have demonstrated the […]

Ketamine for Social Anxiety Disorder: A Randomized, Placebo-Controlled Crossover Trial

Ketamine for Social Anxiety Disorder: A Randomized, Placebo-Controlled Crossover Trial

2 months ago · · 0 comments

– Jerome H Taylor, Angeli Landeros-Weisenberger, Catherine Coughlin, Jilian Mulqueen, Jessica A Johnson, Daniel Gabriel, Margot O Reed, Ewgeni Jakubovski and Michael H Bloch Abstract Many patients with social anxiety disorder (SAD) experience inadequate symptom relief from available treatments. Ketamine is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with a potentially novel mechanism of action for the […]

Ketamine Rapidly Reduces OCD Symptoms

Ketamine Rapidly Reduces OCD Symptoms

3 months ago · · 0 comments

—Lauren LeBano Ketamine can quickly alleviate symptoms of obsessive-compulsive disorder (OCD) in patients with constant intrusive thoughts, and the drug’s effects can last for one to two weeks in certain patients. Researchers reported these findings in a poster presented at the American Psychiatric Association’s (APA) annual meeting. The rapid symptom relief seen from ketamine is […]

The pros and cons of ketamine for Obsessive Compulsive Disorder

The pros and cons of ketamine for Obsessive Compulsive Disorder

3 months ago · · 0 comments

By Tracie White Geuris “Jerry” Rivas, a native of New York, was diagnosed with severe obsessive-compulsive disorder when he was 15. Obsessions with organizing and reorganizing the belongings in his bedroom — posters, comic books, videos — took over most of his life. Forced by germ obsessions to compulsively wash and rewash his hands, he […]

Experimental drug shows promise for quick treatment of postpartum depression

Experimental drug shows promise for quick treatment of postpartum depression

3 months ago · · 0 comments

By MEGHANA KESHAVAN @megkesh and DAMIAN GARDE @damiangarde An experimental drug touted as a breakthrough for treating severe postpartum depression is showing some promising results in a small clinical trial. Sage Therapeutics (SAGE), based in Cambridge, Mass., reported on Tuesday that 7 of the 10 women who took the drug in the trial experienced significant improvement in their depression within […]

Ketamine Infusion Improves Abstinence in Cocaine-Dependent Patients

Ketamine Infusion Improves Abstinence in Cocaine-Dependent Patients

3 months ago · · 0 comments

– Kevin Kunzmann MD Magazine Ketamine infusion, combined with mindfulness-based behavioral changes, has been shown to improve various aspects of treatment outcomes among rehabilitating cocaine-dependent individuals. The new findings from a randomized clinical trial show just a single infusion of the highly potent—yet controversial—NMDA receptor agonist is associated with significant patient improvements in cocaine abstinence at the […]

Single, Repeated, and Maintenance Ketamine Infusions for Treatment-Resistant Depression: A Randomized Controlled Trial

Single, Repeated, and Maintenance Ketamine Infusions for Treatment-Resistant Depression: A Randomized Controlled Trial

3 months ago · · 0 comments

Abstract Objective: Subanesthetic ketamine doses have been shown to have rapid yet transient antidepressant effects in patients with treatment-resistant depression, which may be prolonged by repeated administration. The purpose of this study was to evaluate the antidepressant effects of a single ketamine infusion, a series of repeated ketamine infusions, and prolongation of response with maintenance […]

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